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INTRODUCTION
OUTLINE
  • A01 Molecular Control
  • A02 Structure Construction
  • A03 Function Exploration
ORGANIZATION
  • A01 Molecular Control
  • A02 Structure Construction
  • A03 Function Exploration
MEETINGS
ACHIEVEMENTS
TOPICS
PUBLICATIONS
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Profile
Hisakazu MIHARA,
Professor
Department of Bioengineering, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology
Contact Information
Address: B40, 4259 Nagatsuta-cho, Midori-ku, Yokohama, 226-8501
E-mail: hmihara“at”bio.titech.ac.jp (but replace "at" with "@")
Personal Homepage：http://www.mihara.bio.titech.ac.jp/
Fields of Interest
Peptide, Biopolymers, Nanofiber, Self-Assembly
Professional Experience
1986 Undergraduate & Graduate Research, Kyushu University
1986-1988 Postdoctoral Fellow, The Rockefeller University
1988-1993 Assistant Professor, Kyushu Institute of Technology
1993-1995 Associate Professor, Nagasaki University
1995-2005 Associate Professor, Tokyo Institute of Technology
2005-present Professor, Tokyo Institute of Technology
Education
Dr. Sc., Kyushu University, 1986
Membership of Academic Societies
The Society of Polymer Science, Japan, The Chemical Society of Japan
Awards & Honors
  1. Teshima Research Award (2001)
  2. Fellow, The Royal Society of Chemistry (2005)
Research Project
Construction of Fusion Materials Using Self-Assembling Peptide Nanofibers
Selected Publications
  1. Sawada, T., Mihara, H.
    “Dense Surface Functionalization Using Peptides that Recognize Differences in Organized Structures of Self-Assembling Nanomaterials”,
    Mol. BioSyst., 8, 1264-1274 (2012)

  2. Sawada, T., Tsuchiya, M., Takahashi, T., Tsutsumi, H., Mihara, H.
    “Cell-Adhesive Hydrogels Composed of Peptide NanofibersResponsive to Biological Ions”
    Polymer J., 44, 651-657 (2012)

  3. Miyachi, A., Takahashi, T., Matsumura, S., Mihara, H.
    “Peptide Nanofibers Modified with a Protein by Using Designed Anchor Molecules Bearing Hydrophobic and Functional Moieties”,
    Chem. Eur. J., 16, 6644-6650 (2010).

  4. Suzuki, M., Takahashi, T., Sato, J., Mie, M., Kobatake, E., Mihara, H.
    “Designed Short Peptides that Form Amyloid-Like Fibrils in Coassembly with Amyloid β-Peptide (Aβ) Decrease the Toxicity of Aβ to Neuronal PC12”,
    ChemBioChem, 11, 1525-1530 (2010).

  5. Sawada, T., Takahashi, T., Mihara, H.
    “Affinity-Based Screening of Peptides Recognizing Assembly States of Self-Assembling Peptide Nanomaterials”,
    J. Am. Chem. Soc., 131, 14434-14441 (2009).

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