Associate ProfessorCKazuki FUKUSHIMA, Ph.D.

Research Field: Polymer Synthesis, Functional Polymers, Biodegradable Polymers, Self-Assembly

Professional Experience

2006. 1-5
Visiting Scholar, Department of Chemistry, Boise State University (ID, USA)
2006-2008
JSPS Fellow (DC2/PD)
2007-2008
Visiting Scholar, Department of Chemistry, Stanford University
2008-2009
Postdoctoral Researcher, Department of Chemistry, Stanford University
2009-2011
Postdoctoral Researcher, IBM Almaden Research Center (San Jose, CA)
2011-2016
Assistant Professor, Graduate School of Science and Engineering, Yamagata University
2016-2018
Assistant Professor, Graduate School of Organic Materials Science, Yamagata University
2018-present
Associate Professor, Department of Chemistry and Biotechnology, School of Engineering, The University of Tokyo

Education

B.S., Kyoto Institute of Technology, 2002
M.S., Kyoto Institute of Technology, 2004
Ph.D., Kyoto Institute of Technology, 2007

Memberships of Academic Societies

The Chemical Society of Japan, The Society of Polymer Science of Japan, Japanese Society for Biomaterials, American Chemical Society

Honors and Awards

The Young Scientistsf Prize, The Commendation for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology (MEXT), April 2018
Excellent Presentation Award (Industrial) in the 96th CSJ Annual Meeting, The Chemical Society of Japan, April 2016
Award for Encouragement of Research in Polymer Science, The Society of Polymer Science, Japan, May 2015. 12nd Intelligent-Cosmos Research Incentive Award, Intelligent-Cosmos Foundation, May 2013
The 1st GSC Student Travel Grant Award, Green Sustainable Chemistry Network, Japan, March 2005

List of Selected Publications

  1. Supramolecular Nanofibers Self-assembled from Cationic Small Molecules Derived from Repurposed Poly(ethylene teraphthalate) for Antibiotic Delivery
    Shaoqiong Liu, Kazuki Fukushima, Shrinivas Venkataraman, James L. Hedrick, Yi Yan Yang
    Nanomedicine, 14, 165-172 (2018).
  2. Monoether-tagged Biodegradable Polycarbonate Preventing Platelet Adhesion and Demonstrating Vascular Cell Adhesion: A Promising Material for Resorbable Vascular Grafts and Stents
    Kazuki Fukushima, Yuto Inoue, Yuta Haga, Takayuki Ota, Kota Honda, Chikako Sato, Masaru Tanaka
    Biomacromolecules, 18, 3834?3843 (2017).
  3. Synthesis of Antithrombotic Poly(carbonate-urethane)s through a Sequential Process of Ring-Opening Polymerization and Polyaddition Facilitated by Organocatalysts
    Kazuki Fukushima, Kota Honda, Yuto Inoue, Masaru Tanaka
    Eur. Polym. J., 95, 728-736 (2017).
  4. Biocompatibility and Hemocompatibility Evaluation of Polyether Urethanes Synthesized Using DBU Organocatalyst
    Andere Basterretxea, Yuta Haga, Ana Sanchez-Sanchez, Mehmet Isik, Lourdes Irusta, Masaru Tanaka, *Kazuki Fukushima, *Haritz Sardon
    Eur. Polym. J., 84, 750-758 (2016).
  5. Supramolecular High Aspect Ratio Assemblies with Strong Antifungal Activity Kazuki Fukushima, Shaoqiong Liu, Hong Wu, Amanda C. Engler, Daniel J. Coady, Hareem Maune, Jed Pitera, Alshakim Nelson, Nikken Wiradharma, Shrinivas Venkataraman, Yuan Huang, Weimin Fan, Jackie Y. Ying, *Yi Yan Yang, *James L. Hedrick
    Nat. Commun., 4, 2861 (2013).
  6. Unexpected Efficiency of Cyclic Amidine Catalysts in Depolymerizing Poly(ethylene terephthalate) under Specific Conditions
    Kazuki Fukushima, Daniel J. Coady, Gavin O. Jones, Hamid A. Almegren, Abdullah M. Alabdulrahman, Fares D. Alsewailem, Hans W. Horn, Julia E. Rice, *James L. Hedrick
    J. Polym. Sci. Part A: Polym. Chem., 51, 1606-1611 (2013).
  7. Advanced Chemical Recycling of Poly(Ethylene Terephthalate) through Organocatalytic Aminolysis
    *Kazuki Fukushima, Julien M. Lecuyer, Di S. Wei, Hans W. Horn, Gavin O. Jones, Hamid A. Al-Megren, Abdullah M. Alabdulrahman, Fares D. Alsewailem, Melanie A. McNeil, Julia E. Rice, *James L. Hedrick
    Polym. Chem., 4, 1610-1616 (2013).
  8. Broad-Spectrum Antimicrobial and Biofilm Disrupting Hydrogels: Stereocomplex-driven Supramolecular Assemblies
    Yan Li, Kazuki Fukushima, Daniel J. Coady, Amanda C. Engler, Shaoqiong Liu, Yuan Huang, John S. Cho, Yi Guo, Lloyd S. Miller, Jeremy P. K. Tan, Pui Lai Rachel Ee, Weimin Fan, *Yi Yan Yang,*James L. Hedrick
    Angew. Chem. Int. Ed., 52, 674-678 (2013).
  9. Broad Spectrum Antimicrobial Supramolecular Assemblies with Distinctive Size and Shape
    Kazuki Fukushima, Jeremy P. K. Tan, Peter A. Korevaar, *Yi Yan Yang, *Jed Pitera, Alshakim Nelson, Hareem Maune, Daniel J. Coady, Jane E. Frommer, Amanda C. Engler, Yuan Huang, Kaijin Xu, Zhongkang Ji, Yuan Qiao, Weimin Fan, Lanjuan Li, Nikken Wiradharma, E. W. Meijer, *James L. Hedrick
    ACS Nano, 6, 9191-9199 (2012).
  10. Thermoresponsive Nanostructured Polycarbonate Block Copolymers as Biodegradable Therapeutic Delivery Carriers
    Sung Ho Kim, Jeremy P.K. Tan, Kazuki Fukushima, Fredrik Nederberg, *Yi Yan Yang, Robert M. Waymouth, *James L. Hedrick
    Biomaterials, 32, 5505-5514 (2011).
  11. Biodegradable Nanostructures with Selective Lysis of Microbial Membranes
    Fredrik Nederberg, Ying Zhang, Jeremy P. K. Tan, Kaijin Xu, Huaying Wang, Chuan Yang, Shujun Gao, Xin Dong Guo, Kazuki Fukushima, Lanjuan Li, *James L. Hedrick, *Yi-Yan Yang
    Nature Chem., 3, 409-414 (2011).
  12. Rational Design of Biodegradable Cationic Polycarbonates for Gene Delivery
    Zhan Yuin Ong, Kazuki Fukushima, Daniel J. Coady, *Yi-Yan Yang, *Pui Lai Rachel Ee, *James L. Hedrick
    J. Control Release, 152, 120-126 (2011).
  13. New Catalytic Insights into Acid/Base Conjugates: Highly Selective Bifunctional Catalysts for Ring-Opening Polymerization
    Daniel J. Coady, Kazuki Fukushima, Hans W. Horn, Julia E. Rice, *James L. Hedrick
    Chem. Commun., 47, 3105-3107 (2011).
  14. Organocatalytic Depolymerization of Poly(ethylene terephthalate)
    *Kazuki Fukushima, Olivier Coulembier, Julien M. Lecuyer, Hamid A. Almegren, Abdullah M. Alabdulrahman, Fares D. Alsewailem, Melanie A. Mcneil, Philippe Dubois, Robert M. Waymouth, Hans W. Horn, *Julia E. Rice, *James L. Hedrick
    J. Polym. Sci. Part A: Polymer Chem., 49, 1273-1281 (2011).
  15. A Simple and Efficient Synthesis of Functionalized Cyclic Carbonate Monomers Using A Versatile Pentafluorophenyl Ester Intermediate
    anders, Kazuki Fukushima, Daniel J. Coady, Alshakim Nelson, Masaki Fujiwara, Manabu Yasumoto, *James L. Hedrick
    J. Am. Chem. Soc., 132, 14724-14726 (2010).
  16. Hydrogen Bonding-Enhanced Micelle Assemblies for Drug Delivery
    Sung Ho Kim, Jeremy P. K. Tan, Fredrik Nederberg, Kazuki Fukushima, John Colson, Chuan Yang, *Alshakim Nelson, *Yi-Yan Yang, *James L. Hedrick
    Biomaterials>, 31, 8063-8071 (2010).
  17. A Supramolecularly Assisted Transformation of Block Copolymer Micelles into Nanotubes
    Sung Ho Kim, Fredrik Nederberg, Robert Jakobs, Jeremy P. K. Tan, Kazuki Fukushima, Alshakim Nelson, E. W. Meijer, Yi Yan Yang, *James L. Hedrick
    Angew. Chem. Int. Ed., 48, 4508-4512 (2009).
  18. Organocatalytic Approach to Amphiphilic Comb-Block Copolymers Capable of Stereocomplexation And Self-Assembly
    Kazuki Fukushima, Russell C. Pratt, Fredrik Nederberg, Jeremy P. K. Tan, Yi Yan Yang, Robert M. Waymouth, *James L. Hedrick
    Biomacromolecules, 9, 3051-3056 (2008).
  19. Synthesis and Characterization of Stereoblock Poly(lactic acid)s with Nonequivalent D/L Sequence Ratios
    Kazuki Fukushima, Masayuki Hirata, Yoshiharu Kimura
    Macromolecules, 40, 3049-3055 (2007).
  20. Spiropyran Dimer toward Photo-Switchable Molecular Machine
    Kazuki Fukushima, Aaron J. Vandenbos, *Tomoko Fujiwara
    Chem. Mater., 19, 644-646 (2007).

Reviews & Books

  1. Biodegradable Functional Biomaterials Exploiting Substituted Trimethylene Carbonates and Organocatalytic Transesterification
    *Kazuki Fukushima, Polym. J., 48, 1103-1114 (2016).
  2. Poly(trimethylene carbonate)-Based Polymers Engineered for Biodegradable Functional Biomaterials
    *Kazuki Fukushima, Biomater. Sci., 4, 9-24 (2016)
  3. Stereocomplexed Polylactides (Neo-PLA) as High-Performance Bio-Based Polymers: Their Formation, Properties, and Application
    Kazuki Fukushima, Yoshiharu Kimura, Polym. Int., 55, 626-642 (2006).
  4. Chapter 6; New Routes to Tailor-Made Polyesters
    Kazuki Fukushima, Tomoko Fujiwara, Polymers for Biomedicine: Synthesis, Characterization, and Applications, Ed. by Carmen Scholz, John Wiley & Sons, Inc., pp. 149-189 (2017).